Empowering Health, Defending Wellness

Address:

Yashoda Medicity, Indirapuram & Yashoda Hospital, Kaushambi

Tag: WomenHealth

Dr. Chhavi GuptaBlogWomenHealth
TB admin

Do you Know Tuberculosis can cause infertility in females and males?

Dr. Chhavi Gupta
DM (Infectious disease), AIIMS, New Delhi
Senior Consultant, Yashoda Superpseciality Hospital, Kaushambi

 The association between infection and infertility has been long known. The infections that manifest symptomatically are identified easily and timely and can be managed. However, infections that lead to asymptomatic infections or remain dormant are more damaging as lack of symptoms prevents a patient from seeking timely medical intervention and consequently chronic damage to reproductive organs.

It is always believed by the common man that TB can affect only the lungs, but TB can affect any body part beyond the lung known as extrapulmonary TB (EPTB). TB affecting reproductive organs, also known as Genitourinary TB is responsible for 27.1 per cent cases of EPTB. The exact incidence of female genitourinary TB is not known because of vague symptomatology or asymptomatic cases, lack of sensitive diagnostic tests, and cases are not underreported.  Genital TB mostly spreads from the lungs or other organs via blood or sometimes directly spreads from adjacent organs like abdominal TB or may be sexually transmitted from active genitourinary TB in the partner.

Female Genitourinary TB and Infertility

TB causes both functional and physiological damage to the reproductive system. Genital TB in females affect most commonly fallopian tubes (90% of cases) leading to tubal blockage, and the uterus in 70% of cases resulting in decreased endometrial receptivity for implantation of a fertilized egg; ovaries are affected in 20-25 % of cases resulting in poor egg formation. Apart from affecting organs, Genital Tb also causes disturbance in the immune system, which may interfere with the implantation of fertilized eggs in the uterus. Thus, genital TB in females not only affect conception but also the ability to carry pregnancy. Further, it is important to note that not only genital TB causes infertility but TB affecting any other organ in the body causes malnutrition, immune disturbances, and impaired hormone production which can lead to poor egg formation or secondary amenorrhoea resulting in infertility.

Infertility treatment and risk of TB

As we learned TB is one of the main reasons for infertility but vice versa is there. Reactivation of TB can occur after surgical manipulation, high steroid levels, immune system perturbations, and increased vascularity during ovarian stimulation are thought to be the triggering factors for TB reactivation.

Male Genitourinary TB and Infertility

Genital TB in males predominantly causes structural damage to the male reproductive system. About 10% of patients with male genital TB may present with infertility, and around 4.0–9.1% of such men may have poor semen quality. Sometimes, scarring and fibrosis may persist even after successful treatment of TB. Similar to females, males may also remain asymptomatic or they may present as an unexplained, gradually progressing decline in semen quality or sometimes TB is picked incidentally during diagnostic workup. Sometimes, TB of any other part of the body apart from genital TB can affect the overall health of males leading to malnutrition and oligospermia.

Genital TB is a paucibacillary disease, i.e. number of tuberculosis bacteria that can be detected is very scanty, hence the diagnosis is very difficult. The diagnostic work requires complete investigations like blood test, radiology test, endometrial biopsies or aspirate followed by pathological or microbiological conformation. Sometimes in absence of appropriate diagnostic test, patients end up in taking tuberculosis treatment based on suspicious or misleading diagnostic test, this may be equally harmful as unnecessary tuberculosis treatment may promote drug resistant tuberculosis.

Genital TB is a complex and chronic infection that can affect reproductive system of both males or females resulting in infertility. Early detection and treatment can prevent irreversible damage but being paucibacillary disease, diagnosis remains difficult. With recent advancement in diagnostic test, detailed history and meticulous examination and diagnostic work up is key to success. Couple must seek specialist opinion before starting tuberculosis treatment for infertility.

Urine Infection admin

Understanding Urinary Tract Infections (UTIs): Causes, Symptoms, and Treatment Options

Urinary Tract Infections (UTIs) are common bacterial infections that affect millions of people worldwide, causing discomfort and inconvenience. Despite being prevalent, UTIs are often misunderstood, leading to misconceptions about their causes, symptoms, and treatment. In this blog post, we will delve into the intricacies of UTIs, shedding light on their causes, symptoms, and available treatment options.

Causes of UTIs:

UTIs typically occur when bacteria enter the urinary tract through the urethra and multiply in the bladder. Various factors can increase the risk of developing a UTI, including:
1. Poor hygiene habits.
2. Sexual activity, which can introduce bacteria into the urinary tract.
3. Certain medical conditions, such as diabetes or kidney stones, that interfere with normal urinary function.
4. Structural abnormalities in the urinary tract that make it easier for bacteria to proliferate.

Symptoms of UTIs:

The symptoms of a UTI can vary depending on the part of the urinary tract affected and the severity of the infection. Common symptoms include:
1. Pain or burning sensation during urination.
2. Frequent urge to urinate, even when the bladder is empty.
3. Cloudy or foul-smelling urine.
4. Pain or pressure in the lower abdomen or back.
5. Fatigue or malaise.
6. Fever or chills (in more severe cases).

Treatment Options for UTIs:

The treatment of UTIs typically involves a course of antibiotics to eliminate the underlying bacterial infection. The choice of antibiotic and duration of treatment may vary depending on factors such as the type of bacteria causing the infection and the severity of symptoms. In addition to antibiotics, healthcare providers may recommend:
1. Drinking plenty of water to help flush out bacteria from the urinary tract.
2. Avoiding irritants such as caffeine, alcohol, and spicy foods that can exacerbate symptoms.
3. Using over-the-counter pain relievers such as ibuprofen or acetaminophen to alleviate discomfort.
4. Practicing good hygiene, including wiping from front to back after using the bathroom and urinating after sexual activity.

Preventing UTIs:

While UTIs are common, there are steps you can take to reduce your risk of developing them, including:
1. Drinking plenty of water to maintain urinary tract health.
2. Urinating frequently to flush out bacteria from the urinary tract.
3. Practicing good hygiene, including keeping the genital area clean and dry.
4. Avoiding the use of harsh soaps or douches in the genital area, as they can disrupt the natural balance of bacteria.
5. Urinating after sexual activity to help prevent the introduction of bacteria into the urinary tract.

Conclusion:

UTIs are common bacterial infections that can cause discomfort and inconvenience if left untreated. By understanding the causes, symptoms, and treatment options for UTIs, individuals can take proactive steps to prevent and manage these infections effectively. If you experience symptoms of a UTI, it is essential to seek medical attention promptly to receive appropriate treatment and prevent complications. Consult Dr. Chhavi Gupta, an expert in infectious diseases with qualifications from AIIMS, New Delhi, for personalized care and treatment options at Yashoda Super Speciality Hospital. For appointments, call +91 8851 346 424.