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IBD vs Intestinal Tuberculosis: The Role of the Infectious Disease Specialist

Intestinal Tuberculosis (TB) and Inflammatory Bowel Disease (IBD) are two conditions that can appear strikingly similar in clinical presentations, making diagnosis a challenging process. Differentiating between these two is crucial, as their treatments are entirely different—and a wrong diagnosis can lead to harmful outcomes.

Similar Symptoms, Different Causes

IBD, which includes Crohn’s disease and ulcerative colitis, is an autoimmune condition where the body attacks its own gut lining. Intestinal TB, on the other hand, is a bacterial infection caused by Mycobacterium tuberculosis affecting the gastrointestinal tract.

Common symptoms of both include:

  • Chronic abdominal pain
  • Diarrhea or altered bowel habits
  • Weight loss
  • Low-grade fever
  • GI bleeding

Despite these similarities, the underlying pathology is very different, which is why the expertise of an Infectious Disease (ID) Specialist is essential.

Why Infectious Disease Evaluation is Key

An ID specialist is trained to detect signs of chronic infections like TB that may mimic autoimmune diseases. They conduct targeted investigations including:

  • PCR testing or GeneXpert for TB DNA
  • Histopathology from biopsies
  • Mantoux (Tuberculin) tests and IGRA (Interferon Gamma Release Assays)
  • Radiological imaging (e.g., CT, MRI)

A thorough infectious workup can prevent the dangerous consequence of misdiagnosing intestinal TB as IBD and wrongly starting immunosuppressants, which can allow TB to disseminate.

  • Treatment: A Delicate Balance
  • Intestinal TB is treated with a full course of Anti-Tubercular Therapy (ATT) for 6–9 months.

IBD often requires long-term immunosuppression (steroids, biologics, etc.).

Starting immunosuppressive treatment in a patient with undiagnosed TB can be fatal. Hence, ruling out TB thoroughly before initiating IBD treatment is a standard recommendation, especially in endemic countries like India.

Clinical Clues That Favor TB Over IBD:

  • History of TB exposure or past TB
  • Presence of lung lesions on chest X-ray
  • Shorter duration of illness
  • Involvement of the ileocecal region
  • Presence of caseating granulomas on biopsy

When to Consult an Infectious Disease Specialist

  • When dealing with unexplained chronic GI symptoms
  • When biopsy shows granulomas or features that are not classic for IBD
  • Before starting immunosuppressive treatment in suspected IBD
  • If there is a lack of response to standard IBD therapies

Remember: Not all granulomatous colitis is IBD—some are TB.

Consult an infectious disease expert to avoid misdiagnosis and ensure safe, effective treatment.
👩‍⚕️ Dr. Chhavi GuptaMBBS, MD, DM (AIIMS, New Delhi)Senior Consultant – Infectious Diseases📍 Yashoda Super Speciality Hospital, Kaushambi📞 For Appointments: +91 8851 346 424🌐 drchhavigupta.com

New Year, New You: Health Resolutions for a Better 2025

As the calendar turns to a new year, it’s the perfect opportunity to set meaningful health resolutions that can transform your well-being. Prioritizing your health not only improves your quality of life but also sets the foundation for long-term happiness and success. Here are some practical and achievable health resolutions to embrace in 2025.

  1. Commit to Regular Exercise : Physical activity is crucial for maintaining a healthy body and mind. Whether it’s a daily walk, yoga, or hitting the gym, find an activity you enjoy and make it a part of your routine. Aim for at least 150 minutes of moderate exercise per week to boost cardiovascular health, strengthen muscles, and enhance mental well-being.
  2. Focus on a Balanced Diet : Eating a nutritious, well-balanced diet is one of the best ways to fuel your body. Incorporate more fruits, vegetables, whole grains, lean proteins, and healthy fats into your meals. Limit processed foods, sugary drinks, and excessive salt. Remember, small changes lead to big results over time.
  3. Prioritize Mental Health : Mental health is as important as physical health. Practice mindfulness, meditation, or other stress-relieving activities. Don’t hesitate to seek professional help if you feel overwhelmed. Building a support system of friends and family can also make a significant difference.
  4. Get Vaccinated and Stay Updated : Vaccines are a critical tool in preventing infectious diseases. Ensure you and your family are up to date on all recommended vaccinations, including flu shots. Preventive care saves lives and keeps your community safe.
  5. Stay Hydrated : Proper hydration is often overlooked but essential for overall health. Make it a goal to drink at least 8-10 glasses of water daily. Carry a reusable water bottle as a reminder to stay hydrated throughout the day.
  6. Prioritize Sleep : Quality sleep is vital for physical recovery and mental clarity. Aim for 7-9 hours of uninterrupted sleep each night. Create a bedtime routine, limit screen time before bed, and ensure your sleeping environment is comfortable and free from distractions.
  7. Avoid Smoking and Limit Alcohol : Quitting smoking and reducing alcohol intake are two of the best decisions you can make for your health. Both habits are linked to a range of chronic diseases, including cancer and heart disease. Seek support if needed, and remember, every step toward quitting counts.
  8. Schedule Regular Check-Ups : Preventive healthcare is key to catching potential health issues early. Schedule annual check-ups, dental visits, and screenings appropriate for your age and medical history. Regular consultations with your doctor can help you stay proactive about your health.
  9. Practice Good Hygiene : Hygiene habits like regular handwashing, sanitizing frequently-touched surfaces, and practicing respiratory etiquette can prevent the spread of illnesses. Teach these habits to your family, especially children.
  10. Set Realistic Goals : Start small and build on your successes. Whether it’s losing a few pounds, running a mile, or cooking more meals at home, setting realistic and specific goals makes it easier to stay motivated and track progress.

Conclusion

The new year is a time for renewal and growth. By making your health a priority, you can set the tone for a vibrant and fulfilling 2025. Remember, every small step counts toward a healthier you. If you’re looking for expert guidance on achieving your health goals, consult Dr. Chhavi Gupta, MBBS, MD, DM (AIIMS, New Delhi), Senior Consultant in Infectious Diseases at Yashoda Super Speciality Hospital, Kaushambi.

📞 Book Your Appointment: +91 8851 346 424
🌐 Visit: drchhavigupta.com